About L-methylfolate
Folate
Folate is a B vitamin found in leafy green vegetables, legumes, egg
yolk, and citrus fruit. Folate is an important nutrient and is needed
before and during pregnancy. Folate is an essential nutrient that is
required for DNA replication. Demands for folate increase during
pregnancy because it is needed for growth and development of the fetus.
Dietary supplements and folic acid have to be converted (metabolized)
into the active form of folate, called L-methylfolate.
L-methylfolate
L-methylfolate is the active form of folate and ready to be used by the
body. L-methylfolate provides many benefits to your pregnancy.
These benefits include:
References in Chart:
1 Molloy Anne M, Daly Sean, Mills James L, Kirke Peader N,
Whitehead Alexander S, Ramsbottom Dorothy, Conley Mary R, Weir Donald G,
and Scott John M: Thermalobile variant of 5,10-Methylenetetrahydrofolate
reductase associated with low red-cell folates: implications for folate
intake recommendations. The Lancet 1997;Vol 349:1591-93
2 Botto Lorenzo D, and Yang Quanhe:
5,10-Methylenetetrahydrofolate Reductase Gene Variants and Congenital
Anomalies: A HuGE Review. American Journal of Epidemiology 2000;Vol 151,
No.9:862-77.
3 Lamers, Yvonne, Prinz-Langenohl, Bramswig Susanne, and
Pietrzik Klaus: Red blood cell folate concentrations increase more after
supplementation with [6S]-5-methyltetrahydrofolate than folic acid in
women of childbearing age. Am J Clin Nutr 2006;84:156-61
4 Akoglu, M Schrott, H Bolouri, A Jaffari, E Kutschera, WF
Capsary and D Faust: The Folic Acid Metabolite
L-5-Methyltetrahydrofolate Effectively Reduces Total Serum Homocysteine
Level in Orthotopic Liver Transplant Recipients: A Double-Blind Placebo
Controlled Study. European Journal of Clinical Nutrition (2007), 1-6
5 Willems FF, Boers GH, Blom HJ, et al. Pharmacokinetic Study
on the Utilization of 5-methyltetrahydrofolate and Folic Acid in
Patients with Coronary Artery disease. Br. J Pharmacol 2004;141:825-830
NéevoDHA® is a food for special dietary use in women who are pregnant or lactating.