About L-methylfolate
Folate
Folate is a B vitamin found in leafy green vegetables, legumes, egg yolk, and citrus fruit. Folate is an important nutrient and is needed before and during pregnancy. Folate is an essential nutrient that is required for DNA replication. Demands for folate increase during pregnancy because it is needed for growth and development of the fetus. Dietary supplements and folic acid have to be converted (metabolized) into the active form of folate, called L-methylfolate.
L-methylfolate
L-methylfolate is the active form of folate and ready to be used by the body. L-methylfolate provides many benefits to your pregnancy.
These benefits include:
References in Chart:
1 Molloy Anne M, Daly Sean, Mills James L, Kirke Peader N, Whitehead Alexander S, Ramsbottom Dorothy, Conley Mary R, Weir Donald G, and Scott John M: Thermalobile variant of 5,10-Methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations. The Lancet 1997;Vol 349:1591-93
2 Botto Lorenzo D, and Yang Quanhe: 5,10-Methylenetetrahydrofolate Reductase Gene Variants and Congenital Anomalies: A HuGE Review. American Journal of Epidemiology 2000;Vol 151, No.9:862-77.
3 Lamers, Yvonne, Prinz-Langenohl, Bramswig Susanne, and Pietrzik Klaus: Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than folic acid in women of childbearing age. Am J Clin Nutr 2006;84:156-61
4 Akoglu, M Schrott, H Bolouri, A Jaffari, E Kutschera, WF Capsary and D Faust: The Folic Acid Metabolite L-5-Methyltetrahydrofolate Effectively Reduces Total Serum Homocysteine Level in Orthotopic Liver Transplant Recipients: A Double-Blind Placebo Controlled Study. European Journal of Clinical Nutrition (2007), 1-6
5 Willems FF, Boers GH, Blom HJ, et al. Pharmacokinetic Study on the Utilization of 5-methyltetrahydrofolate and Folic Acid in Patients with Coronary Artery disease. Br. J Pharmacol 2004;141:825-830
NeevoDHA® is a food for special dietary use in women who are pregnant or lactating.